Microfluidic technologies represent a revolution in scientific research and allow biological experiments to be controlled at the nanoliter and microliter scale. Microfluidic technologies allow exquisite control and measurement of hydrodynamics, mechanics, combinatorial reaction complexity, and biomolecular spatial gradients. Novel device configurations can significantly enhance research projects in the areas of blood biology, immunology, oncology, tissue engineering, stem cell biology, biomechanics and mechanobiology, drug and gene delivery, pre-analytical sample processing, and molecular/cellular diagnostics.
While the use of microfluidic devices is prevalent within the Bioengineering or Physics research communities, availability of advanced microfluidic technologies to many biomedical scientists and clinicians is rather limited, due to inconsistent access to facilities, lack of expertise in manufacturing, and lack of training in microfluidics-based research.
The Penn Biomedical Microfluidics Center (PBMC) will provide high value technologies to diverse scientists seeking to take advantage of this growing but highly diverse set of research tools. PBMC utilizes the talents of many investigators at Penn who are expert in microfluidics, micropatterning, and microelectronics for biomedical research.